facilitative transporters
SLC transporters that allow solutes to flow with their electrochemical gradients
FDA
Food and Drug Administration
This refers to drugs that enter the portal blood supply after they are absorbed from the small intestine and are exposed to metabolic enzymes in the liver. If a large portion of the drug is metabolized in this first pass through the liver, then only a smaller portion of the absorbed dose will enter into the systemic circulation.
FMO
Flavin monooxygenase. A microsomal enzyme that catalyzes heteroatom oxygenation of xenobiotics.