XenoTech Products
XenoTech offers one of the most extensive selections of products for drug metabolism-related research, including:
SAFETY, HANDLING AND STORAGEThe products listed on this site are distributed for research purposes only. They have not been approved for therapeutic or diagnostic purposes, or for administration to animals or humans.
Products composed of subcellular fractions (microsomes,
S9, cytosol, etc.) should be stored in an ultra-low freezer (–70°C or colder). A study performed by XenoTech’s scientists and published in a prominent journal demonstrated that our microsomes can be thawed and re-frozen at ultra-low temperatures at least 10 times with
no significant loss of CYP activity.
Pearce R, McIntyre CJ, Madan A, Sanzgiri U, Draper AJ, Bullock P, Cook DC, Burton LA, Latham J, Nevins C and Parkinson A: Effects of freezing, thawing, and storing human liver microsomes on cytochrome P450. Arch Biochem Biophys, 331: 145-169, 1996.
Consequently, any remaining sample can be re-frozen for future use. Care should be taken to keep thawed samples on ice (~4°C) and to return them as quickly as possible to an ultra-low freezer for storage.
Cryopreserved Hepatocytes should be stored in liquid nitrogen vapor (-160°C or colder). They should be thawed in accordance with our thawing protocol, which is shipped with your hepatocytes.
Caution: In the case of human tissue, XenoTech accepts only non-transplantable tissue from donors who test negative for HIV 1 and 2, HTLV, and Hepatitis B and C. However, as a precaution, all human-derived samples should be regarded as a potential biohazard and should be stored, handled and discarded accordingly. Cellular and subcellular fractions are intended for in vitro use only.
REGULATORY COMPLIANCE
All of XenoTech’s products are manufactured and characterized following the principles of GLP regulations and management-approved standard operating procedures.
PRICING INFORMATIONContact us for product price lists for North America. Our global customers are encouraged to contact the
distributor for their location.
PRIMARY SOURCE / BULK DISCOUNTSXenoTech is the primary vendor for several pharmaceutical companies. This type of contractual arrangement offers many benefits to the end user. If you are interested in primary source agreements, please
contact us.