Cryopreserved Beagle Dog Hepatocytes
View ProductsDESCRIPTIONCHARACTERIZATION PROVIDEDRELATED PRODUCTSPRODUCTSDESCRIPTION
Upon thawing, our pooled cryopreserved Beagle dog
hepatocytes remain viable (data shown below) and may be used in suspension for short-term drug
metabolism experiments (we recommend incubations no longer than four hours). When cryopreserved Beagle dog hepatocytes are thawed, isolated and suspended under appropriate conditions, they can be used to evaluate the
in vitro metabolism of drug candidates.
Please note that XenoTech does not recommend cryopreserved dog hepatocytes for use in culture because their attachment to cell culture dishes is unpredictable.
Return to TopCHARACTERIZATION PROVIDED
Characterization data from a representative lot of D1000.H15
Enzyme |
Marker Substrate Reaction |
pmol/cells per inc/min |
Phase I |
7-Ethoxycoumarin O-dealkylation |
251 |
Phase II |
7-Hydroxycoumarin glucuronidation |
70.7 |
Phase II |
7-Hydroxycoumarin sulfation |
78.8 |
Return to TopReturn to TopPRODUCTS
Product No. |
Product |
Gender |
Assured Minimum Yield* |
Amount |
D1000.H15 |
Cryopreserved Beagle Dog Hepatocytes |
Male |
3.5x106 cells |
1.5 mL |
D1000.H45 |
Cryopreserved Beagle Dog Hepatocytes |
Male |
12x106 cells |
4.5 mL |
D1500.H15 |
Cryopreserved Beagle Dog Hepatocytes |
Female |
3.5x106 cells |
1.5 mL |
* AMY is based on experiments performed at XenoTech using XenoTech's
thawing protocol (PDF) and
Hepatocyte Isolation Kit.
Return to TopOrder Fax: 913.227.7171
Order E-mail: info@xenotechllc.com
Call 877.588.7530 (toll-free US and Canada) for pricing and availability.
If ordering outside of North America, please see our Distributor information.