Cryopreserved Monkey Hepatocytes
View ProductsDESCRIPTIONCHARACTERIZATION PROVIDEDRELATED PRODUCTSSAFETY, HANDLING AND STORAGEPRODUCTSDESCRIPTION
Upon thawing, cryopreserved monkey
hepatocytes remain viable (data shown below) and may be used in suspension for short-term drug
metabolism experiments (we recommend incubations no longer than four hours). When cryopreserved monkey hepatocytes are thawed, isolated and suspended under appropriate conditions, they can be used to evaluate the
in vitro metabolism of drug candidates.
Please note that XenoTech does not recommend cryopreserved monkey hepatocytes for use in culture because their attachment to cell culture dishes is unpredictable.
Return to TopCHARACTERIZATION PROVIDED
Characterization data from a representative lot of P2500.H15
Enzyme |
Marker Substrate Reaction |
pmol/cells per inc/min |
Phase I |
7-Ethoxycoumarin O-dealkylation |
139 |
Phase II |
7-Hydroxycoumarin glucuronidation |
96.3 |
Phase II |
7-Hydroxycoumarin sulfation |
72.1 |
Return to TopReturn to TopSAFETY, HANDLING AND STORAGE
Policy statement concerning the safety of non-human primate-derived material
XenoTech manufactures products derived from non-human primate tissue for the purpose of xenobiotic research.
All tissue used to manufacture these products is obtained from reliable sources within the
United States, and is obtained from disease-free (asymptomatic) animals under the care of a veterinarian.
In accordance with federal (USDA) regulations, all non-human primates entering the
United States are placed in quarantine for a period of thirty days.
If an animal is infected with Ebola virus, it would die during the quarantine period, and hence, would not reside in a primate colony in the
United States.
For this reason, Ebola virus testing is not a common procedure in the
United States.
Animals are tested for Simian Herpes B virus (SBV), Simian Retrovirus (SRV), and Simian Immunodeficiency virus (SIV).
All non-human primate tissue utilized at XenoTech is obtained from animals which have tested seronegative for these viruses.Although animals are quarantined and tested for certain infectious diseases, it is not scientifically possible to guarantee that non-human primate-derived material is free of
all infectious agents and poses absolutely no health risk.
Therefore, we strongly caution all researchers who use non-human primate-derived material to treat such material as a potential biohazard, and to observe all national, regional, and local regulations governing the handling of such material.
Even if non-human primate-derived material has been tested for the presence of specific infectious agents by highly sensitive techniques, such as RT-PCR, and found to test negative, the material should still be treated as a potential biohazard.
PRODUCTS
Product No. |
Product |
Gender |
Assured Minimum Yield* |
Amount |
P1000.H15B |
Cryopreserved Rhesus Monkey Hepatocytes |
Male |
6x106 cells |
1.5 mL |
P1000.H15A |
Cryopreserved Rhesus Monkey Hepatocytes |
Male |
4x106 cells |
1.5 mL |
P2000.H15B |
Cryopreserved Cynomolgus Monkey Hepatocytes |
Male |
6x106 cells |
1.5 mL |
P2000.H15A |
Cryopreserved Cynomolgus Monkey Hepatocytes |
Male |
4x106 cells |
1.5 mL |
P3000.H15B |
Cryopreserved Marmoset Monkey Hepatocytes |
Male |
5x106 cells |
1.5 mL |
P3000.H15A |
Cryopreserved Marmoset Monkey Hepatocytes |
Male |
3.5x106 cells |
1.5 mL |
P1500.H15B |
Cryopreserved Rhesus Monkey Hepatocytes |
Female |
6x106 cells |
1.5 mL |
P1500.H15A |
Cryopreserved Rhesus Monkey Hepatocytes |
Female |
4x106 cells |
1.5 mL |
P2500.H15B |
Cryopreserved Cynomolgus Monkey Hepatocytes |
Female |
6x106 cells |
1.5 mL |
P2500.H15A |
Cryopreserved Cynomolgus Monkey Hepatocytes |
Female |
4x106 cells |
1.5 mL |
* AMY is based on experiments performed at XenoTech using XenoTech's
thawing protocol (PDF) and
Hepatocyte Isolation Kit.
Return to TopOrder Fax: 913.227.7171
Order E-mail: info@xenotechllc.com
Call 877.588.7530 (toll-free US and Canada) for pricing and availability.
If ordering outside of North America, please see our Distributor information.