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Cryopreserved IGS Sprague-Dawley Rat Hepatocytes

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CHARACTERIZATION PROVIDED
PRODUCTS

CHARACTERIZATION PROVIDED


Characterization data from a representative lot of R1000.H15

Enzyme

Marker Substrate Reaction

pmol/cells per inc/min

Phase I

7-Ethoxycoumarin O-dealkylation

88.6 ± 4.2

Phase II

7-Hydroxycoumarin glucuronidation

249 ± 47

Phase II

7-Hydroxycoumarin sulfation

292 ± 15

Data are presented as an average ± standard deviation (n=4).

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PRODUCTS


Product No.

Product

Gender

Assured Minimum Yield*

Amount

R1000.H15

Cryopreserved, Pooled IGS Sprague-Dawley Rat Hepatocytes

Male

7x106 cells

1.5 mL

R1000.H45

Cryopreserved, Pooled IGS Sprague-Dawley Rat Hepatocytes

Male

17x106 cells

4.5 mL

R1500.H15

Cryopreserved, Pooled IGS Sprague-Dawley Rat Hepatocytes

Female

7x106 cells

1.5 mL

* AMY is based on experiments performed at XenoTech using XenoTech's thawing protocol (PDF) and Hepatocyte Isolation Kit.

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