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Beagle Dog Lung Subcellular Fractions

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DESCRIPTION
PACKAGING
CHARACTERIZATION PROVIDED
RELATED PRODUCTS
PRODUCTS

DESCRIPTION


As the primary site for the entrance of airborne agents, and as the recipient of all cardiac output, the lungs may provide both first-pass and systemic metabolism of xenobiotics through several enzymatic pathways including both cytochrome P450 and Phase 2 enzymes.

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PACKAGING


Micro­somes
Concentration: 10 mg/mL
Suspension buffer: 250 mM sucrose

S9 fraction
Concentration: 5 mg/mL
Suspension buffer: 50 mM TRIS·HCl (pH 7.4 at 4°C) containing 150 mM KCl and 2 mM EDTA

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CHARACTERIZATION PROVIDED


XenoTech's lung subcellular fractions are characterized for the following activities:

  • NADPH-cytochrome c reductase
  • 7-Ethoxyresorufin O-dealkylation
  • 4-Methylumbelliferone glucuronidation
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RELATED PRODUCTS


XenoTech also offers subcellular fractions of pulmonary tissue from the following toxicologically significant species:

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PRODUCTS


Product No.

Product

Gender

Amount

D1000.P

Pooled Beagle Dog Pulmonary Microsomes

Male

0.5 mL at 10 mg/mL

D1000.PS9

Pooled Beagle Dog Pulmonary S9 Fraction

Male

1.0 mL at 5 mg/mL


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Order Fax: 913.227.7171
Order E-mail: info@xenotechllc.com
Call 877.588.7530 (toll-free US and Canada) for pricing and availability.
If ordering outside of North America, please see our Distributor information.