Golden Syrian Hamster Subcellular Fractions
View Products XenoTech offers pooled liver microsomes, S9 fractions and cytosol from sexually-mature male Golden Syrian hamsters.
DESCRIPTION
PACKAGING
CHARACTERIZATION PROVIDED
PRODUCT DETAILS
PRODUCTS
DESCRIPTION
Liver microsomes contain cytochromes P450, flavin-monooxygenases, carboxylesterases, epoxide hydrolase, UDP-glucuronosyltransferases and other drug-metabolizing enzymes, and are intended for use in
in vitro studies of xenobiotic metabolism.
The
S9 fraction is a mixture of microsomes and cytosol. Accordingly, it contains a wide variety of Phase 1 and Phase 2 enzymes including P450 enzymes, flavin-monooxygenases, carboxylesterases, epoxide hydrolase, UDP-glucuronosyltransferases, sulfotransferases, methyltransferases, acetyltransferases, glutathione
S‑transferases and other drug-metabolizing enzymes.
Liver cytosol contains many xenobiotic metabolizing enzymes including carboxylesterases, soluble epoxide hydrolases, alcohol dehydrogenases, aldehydes oxidases, xanthine oxidases, diamine oxidases, sulfotransferases, glutathione
S‑transferases, etc.
Return to topPACKAGING
MicrosomesConcentration: 20 mg/mL
Suspension buffer: 250 mM sucrose
S9 fractionConcentration: 20 mg/mL
Suspension buffer: 50 mM TRIS
·HCl (pH 7.4 at 4°C) containing 150 mM KCl and 2 mM EDTA
CytosolConcentration: 10 mg/mL
Suspension buffer: 50 mM TRIS
·HCl (pH 7.4 at 4°C) containing 150 mM KCl and 2 mM EDTA
Return to topCHARACTERIZATION PROVIDED
The following lot-specific product information is included with each order of non-human liver microsomes.
- Specific content of cytochrome P450
- Specific content of cytochrome b5
- NADPH-cytochrome c reductase activity
- 7-Ethoxycoumarin O-dealkylation
- Animal Information and Husbandry
Return to topPRODUCT DETAILS
NOMENCLATURE Lak:LVG(SYR)BR
ORIGIN Three members of a litter captured in Syria in 1930 were retained in captivity. It is the progeny of these animals that were first imported to the United States in 1938. Descended from two original colonies acquired by Lakeview in 1949 and 1951. Closed outbred colony since 1951.
COAT COLOR Medium tan.
Return to topPRODUCTS
Product No. |
Product |
Gender |
Amount |
S1000 |
Pooled Golden Syrian Hamster Liver Microsomes |
Male |
0.5 mL at 20 mg/mL |
S1000.S9 |
Pooled Golden Syrian Hamster Liver S9 Fraction |
Male |
1.0 mL at 20 mg/mL |
S1000.C |
Pooled Golden Syrian Hamster Liver Cytosol |
Male |
1.0 mL at 10 mg/mL |
Return to TopOrder Fax: 913.227.7171
Order E-mail: info@xenotechllc.com
Call 877.588.7530 (toll-free US and Canada) for pricing and availability.
If ordering outside of North America, please see our Distributor information.