Treated Animal Liver Subcellular Fractions
XenoTech offers liver subcellular fractions from the following treated species:
Treatment of animals with various xenobiotics causes a marked induction of liver microsomal CYP levels, which, in chronic studies, may be associated with liver and/or thyroid tumor formation. XenoTech provides subcellular fractions from dogs and rats treated with prototypical inducers to serve as positive controls for ex vivo enzyme induction studies.
These products are pooled from many animals to ensure good representation of the inducer and to provide sufficient product availability. The following lot-specific product information is included with each order of microsomes.
- Specific content of cytochrome P450
- Specific content of cytochrome b5
- NADPH-cytochrome c reductase activity
- Activity of the inducible CYP enzyme
- Dosing regimen
- Animal husbandry conditions
Order Fax: 913.227.7171
Order E-mail: info@xenotechllc.com
Call 877.588.7530 (toll-free US and Canada) for pricing and availability.
If ordering outside of North America, please see our Distributor information.