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Calendar of Events
| Date | Event Name |
|---|---|
| Sep 4 - 8, 2010 | ISSX EU Meeting |
| Sep 13 - 17, 2010 | Land O'Lakes Drug Metabolism |
| Nov 14 - 18, 2010 | AAPS 2010 |
Cryopreserved Beagle Dog Hepatocytes
Characterization ProvidedRelated Products
Upon thawing, our pooled cryopreserved Beagle dog hepatocytes remain viable and may be used in suspension for short-term drug metabolism experiments (we recommend incubations no longer than four hours). When cryopreserved Beagle dog hepatocytes are thawed, isolated and suspended under appropriate conditions, they can be used to evaluate the in vitro metabolism of drug candidates.
Please note that XenoTech does not recommend cryopreserved dog hepatocytes for use in culture because their attachment to cell culture dishes is unpredictable.
Characterization Provided
Characterization data from a representative lot of D1000.H15
| Enzyme | Marker Substrate Reaction | pmol/cells per inc/min |
| Phase I | 7-Ethoxycoumarin O-dealkylation | 251 |
| Phase II | 7-Hydroxycoumarin glucuronidation | 70.7 |
| Phase II | 7-Hydroxycoumarin sulfation | 78.8 |
Related Products
- Media
Products
| Product # | Name | Gender | Amount | Assured Minimum Yield |
| D1000.H15 | Cryopreserved Beagle Dog Hepatocytes | Male | 1.5 mL | 3.5x10^6 cells |
| D1000.H45 | Cryopreserved Beagle Dog Hepatocytes | Male | 4.5 mL | 12x10^6 cells |
| D1500.H15 | Cryopreserved Beagle Dog Hepatocytes | Female | 1.5 mL | 3.5x10^6 cells |
