Cryopreserved Human Hepatocytes for Suspension

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Characterization ProvidedSafety, Handling, and StorageRelated Products

XenoTech's cryopreserved human hepatocytes are available in Assured Minimum Yield (AMY) categories, so you can choose the number of viable cells that you need for your experiment.

View available lots here!

Characterization Provided

• CYP1A2 Phenacetin O-dealkylation
• CYP2A6 Coumarin 7-hydroxylation
• CYP2B6 Bupropion hydroxylation
• CYP2C8 Amodiaquine N-dealkylation
• CYP2C9 Diclofenac 4´-hydroxylation
• CYP2C19 S-Mephenytoin 4´-hydroxylation
• CYP2D6 Dextromethorphan O-demethylation
• CYP2E1 Chlorzoxazone 6-hydroxylation
• CYP3A4/5 Testosterone 6β-hydroxylation
• CYP3A4 Midazolam 1´-hydroxylation
• CYP4A11 Lauric acid 12-hydroxylation

Donor information (age, ethnicity, gender, cause of death and infectious disease status)

Safety, Handling, and Storage

Cryopreserved hepatocytes should be stored in liquid nitrogen vapor (-160°C or colder). They should be thawed in accordance with our thawing protocol (PDF), which is shipped with your hepatocytes.

Upon thawing, cryopreserved human hepatocytes remain viable and may be used in suspension for short-term drug metabolism experiments (we recommend incubations no longer than 4 hours). When cryopreserved human hepatocytes are thawed, isolated, and suspended under appropriate conditions, they can be used to evaluate the metabolism of drug candidates.

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