CryostaX Single-Freeze Pooled Cryopreserved Human Hepatocytes

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CryostaX™ is the largest multi-donor pool available prepared using a single-freeze process. 

Pooled human hepatocytes are a preferred test system in many drug discovery and development applications.  Like other pooled human hepatocytes, this pool of 10 provides you with a representative population sample for predictable results; however, our unique process allows pooling after only one freeze. 

Availability of large lots assures long-term reliable results. Each vial contains one pellet (100 uL each) of each donor (n=10).  Each individual is significantly represented in the final preparation.  Assured minimum yield (AMY) is 5 million cells per vials.  We recommend you use our Hepatocyte isolation kit [K2000] for the best results.

Download the datasheet for CryostaX™ here!

Features:

• Single freeze process
• 10 donors
• Large lots
• High-quality data
• Convenient
• Cost-saving (versus pooling your own)
• Allows for future customization of human hepatocytes

Packaging

• 10 x 100 uL = 1.0 mL total volume
• AMY: 5 million cells

Characterization Provided

• % viability
• CYP1A2 Phenacetin O-dealkylation
• CYP2A6 Coumarin 7-hydroxylation
• CYP2B6 Bupropion hydroxylation
• CYP2C8 Amodiaquine N-dealkylation
• CYP2C9 Diclofenac 4´-hydroxylation
• CYP2C19 S-Mephenytoin 4´-hydroxylation
• CYP2D6 Dextromethorphan O-demethylation
• CYP2E1 Chlorzoxazone 6-hydroxylation
• CYP3A4/5 Testosterone 6β-hydroxylation
• CYP3A4 Midazolam 1´-hydroxylation
• UGT 7-Hydroxycoumarin glucuronidation
• SULT 7-Hydroxycoumarin sulfonation

Donor information (age, ethnicity, gender, cause of death and infectious disease status)

Related Products

K2000 Hepatocyte Isolation Kit

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