CryostaX Single-Freeze Pooled Human Hepatocytes

 

CryostaX™ is the largest multi-donor pool available prepared using a patent pending single-freeze process. 

Pooled human hepatocytes are a preferred test system in many drug discovery and development applications.  Like other pooled human hepatocytes, this pool of 10 or 20 provides you with a representative population sample for predictable results; however, our unique process allows pooling after only one freeze. 

Availability of large lots assures long-term reliable results. Each individual is significantly represented in the final preparation. We recommend you use our Hepatocyte isolation kit [K2000] for the best results.

Available Pools & sizes

10-donor pool: 100µL pellets, 1 mL total volume, 5 million cells (HPCH10)
NEW!
20-donor pool: 50µL pellets, 1mL total volume, 5 million cells (HPCH20-50)

View available lots of CryostaX™ and download datasheets here!

 

Features:

  • Patent pending single-freeze process
  • 10 or 20 donor lots available
  • Large lots
  • High-quality data
  • Convenient
  • Cost-saving (versus pooling your own)
  • Completely customizable (design your own 10 or 20-donor pool)

Packaging


10-Donor Pool:

  • 10 x 100uL = 1.0mL total volume
  • AMY: 5 million cells

NEW 20-Donor Pool!

  • 20 x 50µL = 1.0mL total volume
  • AMY: 5 million cells

Characterization Provided

  • % viability
  • CYP1A2 Phenacetin O-dealkylation
  • CYP2A6 Coumarin 7-hydroxylation
  • CYP2B6 Bupropion hydroxylation
  • CYP2C8 Amodiaquine N-dealkylation
  • CYP2C9 Diclofenac 4´-hydroxylation
  • CYP2C19 S-Mephenytoin 4´-hydroxylation
  • CYP2D6 Dextromethorphan O-demethylation
  • CYP2E1 Chlorzoxazone 6-hydroxylation
  • CYP3A4/5 Testosterone 6β-hydroxylation
  • CYP3A4 Midazolam 1´-hydroxylation
  • UGT 7-Hydroxycoumarin glucuronidation
  • SULT 7-Hydroxycoumarin sulfonation

 

Donor information (age, ethnicity, gender, cause of death and infectious disease status)

Product Details

Related Products

K2000 Hepatocyte Isolation Kit

Products

Product #NameGenderAmountAssured Minimum Yield
HPCH10CryostaX™; Single-freeze Cryopreserved Pooled Human Hepatocytes; 10 donorsMixed1.0 mL5 million cells
HPCH20-50CryostaX™; Single-freeze Cryopreserved Pooled Human Hepatocytes; 20 donorsMixed1.0 mL5 million cells