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Calendar of Events
| Date | Event Name |
|---|---|
| Feb 23, 2012 | Webinar: FDA updates |
| Feb 27 - 29, 2012 | Clinically Relevant Drug Transporters |
| Mar 12 - 14, 2012 | SOT 2012 |
| May 6 - 8, 2012 | DDI Marbach Castle |
CryostaX Single-Freeze Pooled Human Hepatocytes
PackagingCharacterization ProvidedProduct DetailsRelated Products
CryostaX™ is the largest multi-donor pool available prepared using a patent pending single-freeze process.
Pooled human hepatocytes are a preferred test system in many drug discovery and development applications. Like other pooled human hepatocytes, this pool of 10 or 20 provides you with a representative population sample for predictable results; however, our unique process allows pooling after only one freeze.
Availability of large lots assures long-term reliable results. Each individual is significantly represented in the final preparation. We recommend you use our Hepatocyte isolation kit [K2000] for the best results.
Available Pools & sizes
10-donor pool: 100µL pellets, 1 mL total volume, 5 million cells (HPCH10)
NEW! 20-donor pool: 50µL pellets, 1mL total volume, 5 million cells (HPCH20-50)
View available lots of CryostaX™ and download datasheets here!
Features:
- Patent pending single-freeze process
- 10 or 20 donor lots available
- Large lots
- High-quality data
- Convenient
- Cost-saving (versus pooling your own)
- Completely customizable (design your own 10 or 20-donor pool)
Packaging
10-Donor Pool:
- 10 x 100uL = 1.0mL total volume
- AMY: 5 million cells
NEW 20-Donor Pool!
- 20 x 50µL = 1.0mL total volume
- AMY: 5 million cells
Characterization Provided
- % viability
- CYP1A2 Phenacetin O-dealkylation
- CYP2A6 Coumarin 7-hydroxylation
- CYP2B6 Bupropion hydroxylation
- CYP2C8 Amodiaquine N-dealkylation
- CYP2C9 Diclofenac 4´-hydroxylation
- CYP2C19 S-Mephenytoin 4´-hydroxylation
- CYP2D6 Dextromethorphan O-demethylation
- CYP2E1 Chlorzoxazone 6-hydroxylation
- CYP3A4/5 Testosterone 6β-hydroxylation
- CYP3A4 Midazolam 1´-hydroxylation
- UGT 7-Hydroxycoumarin glucuronidation
- SULT 7-Hydroxycoumarin sulfonation
Donor information (age, ethnicity, gender, cause of death and infectious disease status)
Product Details
Related Products
K2000 Hepatocyte Isolation Kit
Products
| Product # | Name | Gender | Amount | Assured Minimum Yield |
| HPCH10 | CryostaX™; Single-freeze Cryopreserved Pooled Human Hepatocytes; 10 donors | Mixed | 1.0 mL | 5 million cells |
| HPCH20-50 | CryostaX™; Single-freeze Cryopreserved Pooled Human Hepatocytes; 20 donors | Mixed | 1.0 mL | 5 million cells |
