Monkey Subcellular Fractions

XenoTech offers multiple subcellular fractions derived from monkey liver tissue of the following sexually-mature species:

• Cynomolgus
• Rhesus

Subcellular fractions from untreated animals are intended for in vitro studies of xenobiotic metabolism, such as those used to support drug safety studies in laboratory animals and studies of species, strain and gender differences in drug metabolism. Products are pooled to yield average results and are produced in large lots to assure availability. These products are provided at constant protein concentrations.

Policy Statement Concerning the Safety of Non-human Primate-derived Material

XenoTech manufactures products derived from non-human primate tissue for the purpose of xenobiotic research. All tissue used to manufacture these products is obtained from reliable sources within the United States, and is obtained from disease-free (asymptomatic) animals under the care of a veterinarian.

In accordance with federal (USDA) regulations, all non-human primates entering the United States are placed in quarantine for a period of thirty days. If an animal is infected with Ebola virus, it would die during the quarantine period, and hence, would not reside in a primate colony in the United States. For this reason, Ebola virus testing is not a common procedure in the United States. Animals are tested for Simian Herpes B virus (SBV), Simian Retrovirus (SRV), and Simian Immunodeficiency virus (SIV). All non-human primate tissue utilized at XenoTech is obtained from animals which have tested seronegative for these viruses.

Although animals are quarantined and tested for certain infectious diseases, it is not scientifically possible to guarantee that non-human primate-derived material is free of all infectious agents and poses absolutely no health risk. Therefore, we strongly caution all researchers who use non-human primate-derived material to treat such material as a potential biohazard, and to observe all national, regional, and local regulations governing the handling of such material. Even if non-human primate-derived material has been tested for the presence of specific infectious agents by highly sensitive techniques, such as RT-PCR, and found to test negative, the material should still be treated as a potential biohazard.

Please note:  XenoTech complies with all regulations promulgated by the Convention on International Trade in Endangered Species (CITES). Accordingly, special permits and arrangements must be made to ship all primate products internationally.  Customers in Europe and Japan should contact our distributor nearest you for information on pricing and availability.