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Date Event Name
May 23, 2012 Webinar: PBPK modeling

Transporter Membranes

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ABC transporter involvement can have a significant effect on the absorption, distribution, metabolism and excretion (ADME) of compounds and can implicate drug-drug interactions. By examining the interaction of the multidrug transporters with pharmacological and toxic agents, a prediction for the cellular and tissue distribution of these compounds can be achieved.

SOLVO assays cover the entire passive permeability space, with the ATPase most suitable for high and intermediate permeability compounds and the Vesicular Transport suitable for low permeability compounds.

Products

Product #NameTransporterType
SB1001SB MDR1 Sf9 ATPaseMDR1Membranes for ATPase Assays
SB1002SB rat Mdr1 Sf9 ATPaserat Mdr1bMembranes for ATPase Assays
SB1003SB MRP1 Sf9 ATPaseMRP1Membranes for ATPase Assays
SB1004SB MRP1 Sf9 Vesicular TransportMRP1Membranes for Vesicular Transport Assays
SB1005SB MRP2 Sf9 ATPaseMRP2Membranes for ATPase Assays
SB1006SB MRP2 Sf9 Vesicular TransportMRP2Membranes for Vesicular Transport Assays
SB1008SB BSEP Sf9 Vesicular TransportBSEPMembranes for Vesicular Transport Assays
SB1009SB mouse Bsep Sf9 Vesicular Transportmouse BsepMembranes for Vesicular Transport Assays
SB1010SB MRP3 Sf9 ATPaseMRP3Membranes for ATPase Assays
SB1011SB MRP3 Sf9 Vesicular TransportMRP3Membranes for Vesicular Transport Assays
SB1013SB MRP5 HEK Vesicular TransportMRP5Membranes for Vesicular Transport Assays
SB1015SB BCRP HAM Sf9 Vesicular TransportBCRPMembranes for Vesicular Transport Assays
SB1018SB BCRP M ATPaseBCRPMembranes for ATPase Assays
SB1019SB BCRP M Vesicular TransportBCRPMembranes for Vesicular Transport Assays
SB1020SB BCRP R482G Sf9 ATPaseBCRPMembranes for ATPase Assays
SB1021Sf9 Controls
SB1022BCRP-M Controls
SB1023BCRP-HEK Controls
SB1024MDR1, MRP & BSEP Sf9 Controls
SB1026MultiDrugQuant Assay KitMDR1/MRP1Kit
SB1027BCRP HAM Sf9 Controls
SB1028MDR1 Sf9 Controls
SB1029SB MDR1 K Vesicular TransportMDR1Membranes for Vesicular Transport Assays
SB1030SB-MRP4-LLC-PK1-VTMRP4Membranes for Vesicular Transport Assays
SB1031SB-LLC-PK1-CTRLControl 
SB1032SB-ratMrp2-HEK293-VTratMrp2Membranes for Vesicular Transport Assays
SB1033SB ratMdr1b sf9 VTratMdr1bMembranes for Vesicular Transport Assays
SB1034SB K CTRL Controls