XenoTech, LLC - Publications

Aldehyde Oxidase (AO)

item name

Beedham C, Miceli JJ and Obach RS (2003) Ziprasidone metabolism, aldehyde oxidase, and clinical implications. J Clin Psychopharmacol 23:229-232.
Beedham C (2002) Molybdenum hydroxylases, in: Enzyme Systems that Metabolise Drugs and Other Xenobiotics (Ioannides C ed), pp 147-188, John Wiley & Sons, Ltd., New York, NY.
Lake BG, Ball SE, Kao J, Renwick AB, Price RJ and Scatina JA (2002) Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase. Xenobiotica 32:835-847.
Renwick AB, Ball SE, Tredger JM, Price RJ, Walters DG, Kao J, Scatina JA, Lake BG (2002) Inhibition of zaleplon metabolism by cimetidine in the human liver: in vitro studies with subcellular fractions and precision-cut liver slices. Xenobiotica 32:849-862.
Kawashima K, Hosoi K, Naruke T, Shiba T, Kitamura M and Watabe T (1999) Aldehyde oxidase dependent marked species difference in hepatic metabolism of the sedative hypnotic zaleplon, between monkeys and rats. Drug Metab Dispos 27:422-428 1999.
Sugihara K, Kitamura S and Tatsumi K (1996) Involvement of mammalian liver cytosols and aldehyde oxidase in reductive metabolism of zonisamide. Drug Metab Dispos 24:199-202.