Contact Us
Search website   
 PUBLICATIONS

» Back to All Publication Categories
1-20 | 21-32

Drug Metabolism

Ascendingitem name
Wang MW, Saulter JY, Usuki E, Cheung Y-L, Hall M, Bridges AS, Loewen G, Parkinson OT, Stephens CE, Allen JL, Zeldin DC, Boykin DW, Tidwell RR, Parkinson A, Pain MF and Hall JE
(2006) CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methlamidoxime]. Drug Metab Dispos 34: 1985-1994.
Ndikum-Moffor FM and Roberts SM
(2003) Cocaine-protein targets in mouse liver. Biochem Pharmacol 66:105-113.
Beedham C
(2002) Molybdenum hydroxylases, in: Enzyme Systems that Metabolise Drugs and Other Xenobiotics (Ioannides C ed), pp 147-188, John Wiley & Sons, Ltd., New York, NY.
Parkinson A
(2001) Biotransformation of Xenobiotics, in:  Casarett & Doull’s Toxicology: The Basic Science of Poisons (Klaassen CD ed), pp 133-224, McGraw-Hill, Inc.,  New York City, NY.
Boess F, Ndikum-Moffor FM, Boelsterli UA, Roberts SM
(2000) Effects of cocaine and its oxidative metabolites on mitochondrial respiration and generation of reactive oxygen species. Biochem Pharmacol 60:615-623.
De Wildt SN, Kearns GL, Leeder JS and van den Anker JN
(1999) Cytochrome P450 3A: ontogeny and drug disposition. Clin Pharmacokinet 37:485-505.
Emary WB, Toren PC, Mathews B and Huh K
(1998) Disposition and Metabolism of Rifapentine, a Rifamycin Antibiotic, in Mice, Rats and Monkeys. Drug Metab Dispos 26:725-731.
Juchau MR, Boutelet-Bochan H and Huang Y
(1998) Cytochrome P450 dependent biotransformation of xenobiotics in human and rodent embryonic tissues. Drug Metab Rev 30:541-568.
Lee RP, Parkinson A and Forkert PG
(1998) Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes. Drug Metab Dispos 26:60-65.
Lewis DF and Pratt JM
(1998) The P450 catalytic cycle and oxygenation mechanism. Drug Metab Rev 30:739-786.
Lewis DF, Ioannides C and Parke DV
(1998) An improved and updated version of the compact procedure for the evaluation of P450-mediated chemical activation. Drug Metab Rev 30:709-737.
Ndikum-Moffor FM, Munson JW, Bokinkere NK, Brown JL, Richards N and Roberts SM
(1998) Immunochemical detection of hepatic cocaine-protein adducts in mice. Chem Res Toxicol 11:185-192.
Ndikum-Moffor FM, Schoeb TR and Roberts SM
(1998) Liver toxicity from norcocaine nitroxide, an N-oxidative metabolite of cocaine. J Pharmacol Exp Ther 284:413-419.
Reith K, Keung A, Toren PC, Cheng L, Eller MG and Weir SJ
(1998) Disposition and metabolism of 14C-rifapentine in healthy volunteers. Drug Metab Dispos 26:732-738.
Usuki E, Van der Schyf CJ and Castagnoli N Jr
(1998) Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP. Drug Metab Rev 30:809-826.
Avent KM, Riker RR, Fraser GL, Van der Schyf CJ, Usuki E and Pond SM
(1997) Metabolism of haloperidol to pyridinium species in patients receiving high doses intravenously: Is HPTP an intermediate? Life Sci 61:2383-2390.
Ball S and Borman N
(1997) Pharmacogenetics and drug metabolism. Nature Biotechnol 15:925-926.
Beedham C
(1997) The role of non-P450 enzymes in drug oxidation. Pharm World Sci 19:255-263.
Guengerich FP
(1997) Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species. Chem Biol Interact 106:161-182.
Avent KM, Usuki E, Eyles DW, Keeve R, Van der Schyf CJ, Castagnoli N and Pond SM
(1996) Haloperidol and its tetrahydropyridine derivative (HPTP) are metabolized to potentially neurotoxic pyridinium species in the baboon. Life Sci 59:1473-1482.
1-20 | 21-32
» Back to All Publication Categories
Home | Products | Contract Services | Resource Library | Calendar Of Events | About XenoTech | contact us