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Enzyme Regulation

Ascendingitem name
Rockett JC, Esdaile DJ and Gibson GG
(1999) Differential gene expression in drug metabolism and toxicology: practicalities, problems and potential. Xenobiotica 29:655-691.
Sandig G, Kärgel E, Menzel R, Vogel F, Zimmer T and Schunck WH
(1999) Regulation of endoplasmic reticulum biogenesis in response to cytochrome P450 overproduction. Drug Metab Rev 31:393-410.
Savas Ü, Griffin KJ and Johnson EF
(1999) Molecular mechanisms of cytochrome-P450 induction by xenobiotics: An expanded role for nuclear hormone receptors. Mol Pharmacol 56:851-857.
Waxman DJ
(1999) P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. Arch Biochem Biophys 369:11-23.
Kemper B
(1998) Regulation of cytochrome P450 gene transcription by phenobarbital. Prog Nucleic Acid Res Mol Biol 61:23-64.
Morgan ET, Sewer MB, Iber H, Gonzalez FJ, Lee YH, Tukey RH, Okino S, Vu T, Chen YH, Sidhu JS and Omiecinski CJ
(1998) Physiological and pathophysiological regulation of cytochrome P450. Drug Metab Dispos 26:1232-1240.
Smith G, Stubbins MJ, Harries LW and Wolf CR
(1998) Molecular genetics of the human cytochrome P450 monooxygenase superfamily. Xenobiotica 28:1129-1165.
Honkakoski P and Negishi M
(1997) The structure, function and regulation of cytochrome P450 2A enzymes. Drug Metab Rev 29:997-1096.
Morgan ET
(1997) Regulation of cytochromes P450 during inflammation and infection. Drug Metab Rev 29:1129-1188.
Thompson TN
(1997) Experimental models for evaluating enzyme induction potential of new drug candidates in animals and humans and a strategy for their use. Adv Pharmacol 43:205-229.
Waterman MR
(1996) Introduction: transcription and regulation of activities of cytochromes P450 metabolizing endogenous substrates. FASEB J 10:1455.
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