XenoTech, LLC - Publications

Inhibitors--Specificity and Selectivity

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Ogilvie BW, Zhang D, Li W, Rodrigues AD, Gipson AE, Holsapple J, Toren P and Parkinson A (2006) Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: Implications for drug-drug interactions. Drug Metab Dispos 34:191-197.
Clarke SE (1998) In vitro assessment of human cytochrome P450. Xenobiotica 28:1167-1202.
Lin JH and Lu AY (1998) Inhibition and induction of cytochrome P450 and the clinical implications. Clin Pharmacokinet 35:361-390.
Pelkonen O, Mäenpää J, Taavitsainen P, Rautio A and Raunio H (1998) Inhibition and induction of human cytochrome P450 (CYP) enzymes. Xenobiotica 28:1203-1253.
Draper A, Madan A and Parkinson A (1996) Inhibition of coumarin 7-hydroxylation (CYP2A6) by commonly used P450 inhibitors. Arch Biochem Biophys 341:47-61.
Heath TG, Massad DD, Carroll JI, Mathews BS, Chang J, Scott DO, Kuo BS and Toren PC (1995) Quantification of a dual angiotensin I-converting enzyme-neutral endopeptidase inhibitor and the active thiol metabolite in dog plasma by high performance liquid chromatography with UV absorbance detection. Journal of Chromatography B: Biomedical Applications 670:91.