XenoTech, LLC - Publications

Microsomes

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Parkinson A, Pearce R, Madan A and Forster J (1997) Availability and preservation of human tissues, and the use of human liver microsomes in drug metabolism research. In: The Use of Human In Vitro Systems to Support Preclinical Safety Assessment. (eds. Sundwall A, Alvan G, Lindgren E, Moldeus P, Salmonsson T and Sjoberg P). 17-28 Tryckgruppen, Stockholm, Sweden.
Pearce R, McIntyre CJ, Madan A, Sanzgiri U, Draper AJ, Bullock P, Cook DC, Burton LA, Latham J, Nevins C and Parkinson A (1996) Effects of freezing, thawing, and storing human liver microsomes on cytochrome P450. Arch Biochem Biophys 331:145-169.
Galetin A and Houston JB (2006) Intestinal and hepatic metabolic activity of five cytochrome P450 enzymes: impact on prediction of first-pass metabolism. J Pharmacol Exp Ther 318:1220-1229.