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Species Differences

Ascendingitem name
Kawashima K, Hosoi K, Naruke T, Shiba T, Kitamura M and Watabe T
(1999) Aldehyde oxidase dependent marked species difference in hepatic metabolism of the sedative hypnotic zaleplon, between monkeys and rats. Drug Metab Dispos 27:422-428 1999.

Emary WB, Toren PC, Mathews B and Huh K
(1998) Disposition and Metabolism of Rifapentine, a Rifamycin Antibiotic, in Mice, Rats and Monkeys. Drug Metab Dispos 26:725-731.

Sugihara K, Kitamura S and Tatsumi K
(1996) Involvement of mammalian liver cytosols and aldehyde oxidase in reductive metabolism of zonisamide. Drug Metab Dispos 24:199-202.

Gemzik B, Jacobs S, Jennings S, Veltman J and Parkinson A
(1992) Species differences in 5α-androstane-3β, 17β-diol hydroxylation by rat, monkey and human prostate microsomes. Arch Biochem Biophys 296:374-383.

Pearce R, Greenway D and Parkinson A
(1992) Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation. Arch Biochem Biophys 298:211-225.

Eberhart D, Gemzik B, Halvorson R and Parkinson A
(1991) Species Differences in the Toxicity and Cytochrome P450 IIIA-Dependent Metabolism of Digitoxin. Mol Pharm 40:859-867.

Smith GS, Watkins J, Klaassen C, Rozman K, Thompson T and Harvey M
(1984) Oxidative and conjugative metabolism of xenobiotics by livers of cattle, sheep, swine and rats. J Anim Sci 58:386-395.

Gregus Z, Watkins J, Thompson T, Harvey M, Rozman K and Klaassen C
(1983) Hepatic phase I and phase II biotransformation in quail and trout: comparison to other species commonly used in toxicity testing. Toxicol Appl Pharmacol 67:430-441.

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